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include self-induced vomiting or laxative use. Because anorexia can result in a threat to health and life, inpatient hospitalization is needed in severe cases. Pediatric psychologists working in hospital settings are often involved in the diagnosis, treatment, and research of anorexia nervosa. The etiology, symptoms, and treatment of anorexia reflect the biopsychosocial nature of the disorder and clinical psychology s response to it. Anorexia and other eating disorders may have a genetic component with a 4 to 5 times higher incidence in first-degree relatives (Striegal-Moore, 2000; Strober & Humphrey, 1987). Anorexia per se might not be inherited, yet factors such as personality, impulsivity, body shape, impulse control, anxiety, and other characteristics that might place someone at greater risk for developing an eating disorder may be heritable factors (Fairburn & Brownell, 2002). Once an eating disorder begins, neurochemical factors may perpetuate the problem. Some have suggested that the functioning of the hypothalamus via neurotransmitters such as dopamine, serotonin, and norepinephrine might be involved in anorexia nervosa (Hsu, 1990; Polivy & Herman, 2002). Starvation itself also leads to irrational and rigid thinking, which further perpetuates the problem. Psychological factors including a lack of perceived control in life, poor self-esteem, stress, anxiety, and depression also play a role in the development and course of the illness (Fairburn & Brownell, 2002; Striegal-Moore, Silberstein, & Rodin, 1993). Social factors such as cultural ideals of thinness and beauty play a role in motivating the anorexic s relentless pursuit of thinness (Brownell, 1991a, 1991b; Pike & Rodin, 1991; Striegal-Moore, Silberstein, & Rodin, 1986). Intervention approaches include tube and/or intravenous feeding in medical emergencies, high-calorie liquid diets, and medication to assist with anxiety, depression, and compulsive symptoms. Individual, family, and group psychotherapy

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Despite this fact, these meta-analyses produce ndings and conclusions that are far superior to those produced by the traditional narrative subjective method Many other journals have shown the same increase over time in the number of meta-analyses published Many of these journals, such as Journal of Applied Psychology, had traditionally published only individual empirical studies and had rarely published reviews up until the advent of meta-analysis in the late 1970s These journals began publishing meta-analyses because meta-analyses came to be viewed not as mere reviews, but as a form of empirical research in themselves Between 1978 and 1997 Journal of Applied Psychology published 60 metaanalysis-based articles These 60 articles contained a total of 1,647 separate meta-analyses As a result of this change, the.

Neuroticism Personality has long been thought to play a role in the development of and adaptation to a host of chronic illnesses, including arthritis-related conditions (Af eck, Tennen, Urrows, & Higgins, 1992) Early empirical work aimed at determining whether certain personality attributes were more prevalent among individuals with particular medical disorders relative to other groups In contrast, more recent research has focused on identifying individual differences in personality within diagnostic groups that contribute to disease course One personality characteristic that has particular relevance for a biopsychosocial understanding of adaptation among those with chronic pain is neuroticism, or the dispositional tendency to experience negative emotions.

Proof I (X1 , X2 , . . . , Xn ; Y ) = H (X1 , X2 , . . . , Xn ) H (X1 , X2 , . . . , Xn |Y )

Because individuals high in neuroticism report an increased frequency of stressful experiences (Bolger & Schilling, 1991), and because the experience of stress may enhance disease activity and symptoms of chronic pain (Zautra, Burleson, Matt, Roth, & Borrows, 1994), neuroticism may be especially problematic for those with a musculoskeletal condition In fact, among individuals with RA, neuroticism has been associated with poor self-rated functional status (Radanov, Schwarz, & Frost, 1997), more intense pain (Af eck et al, 1992), and mental health problems (Fyrand, Wichstrom, Moum, Glennas, & Kvien, 1997) A neurotic disposition is also likely to play a role in adaptation to OA and FM, and although few studies have investigated it, the available data do point to this possibility For instance, patients with FM who score high in neuroticism are more frustrated with their physicians than those low in neuroticism (Walker et al, 1997).

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